contestada

A patient produced 1500 mL of urine in a 24-hour period. This patient had a urine creatinine concentration of 10 mmol/L and a plasma creatinine concentration of 100 mmol/L. Calculate the creatinine clearance in mL/min.

Respuesta :

icetornato

To calculate creatinine clearance, you can use the following formula:

Creatinine Clearance

=

Urine Flow Rate

Ă—

Urine Creatinine Concentration

Plasma Creatinine Concentration

Creatinine Clearance=

Plasma Creatinine Concentration

Urine Flow RateĂ—Urine Creatinine Concentration

​

First, we need to convert the urine flow rate from mL/day to mL/min:

Urine Flow Rate

=

1500

mL

24

hours

Ă—

1

hour

60

min

=

1500

24

Ă—

60

mL/min

=

1.0417

mL/min

Urine Flow Rate=

24 hours

1500 mL

​

Ă—

60 min

1 hour

​

=

24Ă—60

1500

​

 mL/min=1.0417 mL/min

Now, we can calculate the creatinine clearance:

Creatinine Clearance

=

1.0417

mL/min

Ă—

10

mmol/L

100

mmol/L

Creatinine Clearance=

100 mmol/L

1.0417 mL/minĂ—10 mmol/L

​

Creatinine Clearance

=

1.0417

Ă—

10

100

mL/min

Creatinine Clearance=

100

1.0417Ă—10

​

 mL/min

Creatinine Clearance

=

0.10417

mL/min

Creatinine Clearance=0.10417 mL/min

So, the creatinine clearance is approximately

0.10417

mL/min

0.10417 mL/min.

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